Unravelling Competitive Interactions between Polymer Side Chains and End Groups with β-Cyclodextrin

Katharina Ziegler; Yorick Post; André H Gröschel; Bart Jan Ravoo

doi:10.1002/marc.202400081

Unravelling Competitive Interactions between Polymer Side Chains and End Groups with β-Cyclodextrin

Macromol Rapid Commun. 2024 May 5:e2400081. doi: 10.1002/marc.202400081. Online ahead of print.

Authors

Katharina Ziegler¹, Yorick Post¹, André H Gröschel², Bart Jan Ravoo¹

Affiliations

¹ Organic Chemistry Institute and Center for Soft Nanoscience, University of Münster, Corrensstraße 40, 48149, Münster, Germany.
² Bavarian Center for Battery Technology (BayBatt) and Bavarian Polymer Institute (BPI), University of Bayreuth, Universitätsstr. 30, 95448, Bayreuth, Germany.

PMID: 38704746
DOI: 10.1002/marc.202400081

Abstract

This study investigates unexpected competitive host-guest interactions of β-cyclodextrin (β-CD), which can occur with polymers in aqueous solution, using the examples of the two polymers poly(oligo(ethylene glycol) methyl ether methacrylate) and poly(glycerol mono methacrylate). Systematic structural modifications of the polymer provide insight into the host-guest interaction with β-CD and the competition between side chains and end groups such as hydrophobic end groups remaining from reversible addition fragmentation chain transfer polymerization or intentionally implemented molecular recognition units such as arylazopyrazole photoswitches.

Keywords: host–guest chemistry; isothermal titration calorimetry; molecular photoswitches; polyacrylates; supramolecular interactions.

Grants and funding

CRC 1459/Deutsche Forschungsgemeinschaft