Abstract
A dual NIR fluorescent probe Cy-ND is developed for viscosity sensing with λex/em = 766/806 nm, making it apt for biological analysis, whose response is validated through DFT and TDDFT computations. Cy-ND successfully detected viscosity changes amidst acute alcohol-induced liver injury and liver ischemia-reperfusion injury.
MeSH terms
-
Animals
-
Carbocyanines / chemistry
-
Density Functional Theory
-
Fluorescent Dyes* / chemical synthesis
-
Fluorescent Dyes* / chemistry
-
Humans
-
Liver / diagnostic imaging
-
Liver Diseases, Alcoholic / diagnostic imaging
-
Mice
-
Optical Imaging
-
Reperfusion Injury / diagnostic imaging
-
Viscosity
Substances
-
Fluorescent Dyes
-
Carbocyanines