Multiple-component covalent organic frameworks for simultaneous extraction and determination of multitarget pollutants in sea foods

Jing Gong; Yanlong Chen; Wenwei A; Xingyuan Zhang; Juanqiong Ma; Zhiyong Xie; Pei Li; Aihua Huang; Shusheng Zhang; Qiongfeng Liao

doi:10.1016/j.jhazmat.2024.134563

Multiple-component covalent organic frameworks for simultaneous extraction and determination of multitarget pollutants in sea foods

J Hazard Mater. 2024 May 9:472:134563. doi: 10.1016/j.jhazmat.2024.134563. Online ahead of print.

Authors

Jing Gong¹, Yanlong Chen², Wenwei A³, Xingyuan Zhang¹, Juanqiong Ma¹, Zhiyong Xie⁴, Pei Li⁵, Aihua Huang¹, Shusheng Zhang⁶, Qiongfeng Liao⁷

Affiliations

¹ School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
² School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China. Electronic address: chenyl8909@163.com.
³ Guangzhou Customs District Technology Center, Guangzhou, Guangdong Province, 510623, China.
⁴ School of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong Province, 518106, China.
⁵ Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China.
⁶ Center for Modern Analysis and Gene Sequencing, Zhengzhou University, No. 100 of Kexue Road, Zhengzhou 450001, China.
⁷ School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510006, China. Electronic address: zyfxliao@gzucm.edu.cn.

PMID: 38735186
DOI: 10.1016/j.jhazmat.2024.134563

Abstract

Persistent organic pollutants (POPs), such as perfluoroalkyl and polyfluoroalkyl substances (PFASs), polychlorinated biphenyls (PCBs), and bisphenols (BPs), have been raising global concerns due to their toxic effects on environment and human health. The monitoring of residues of POPs in seafood is crucial for assessing the accumulation of these contaminants in the study area and mitigating potential risks to human health. However, the diversity and complexity of POPs in seafood present significant challenges for their simultaneous detection. Here, a novel multi-component fluoro-functionalized covalent organic framework (OH-F-COF) was designed as SPE adsorbent for simultaneous extraction POPs. On this basis, the recognition and adsorption mechanisms were investigated by molecular simulation. Due to multiple interactions and large specific surface area, OH-F-COF displayed satisfactory coextraction performance for PFASs, PCBs, and BPs. Under optimized conditions, the OH-F-COF sorbent was employed in a strategy of simultaneous extraction and stepwise elution (SESE), in combination with HPLC-MS/MS and GC-MS method, to effectively determined POPs in seafood collected from coastal areas of China. The method obtained low detection limits for BPs (0.0037 -0.0089 ng/g), PFASs (0.0038 -0.0207 ng/g), and PCBs (0.2308 -0.2499 ng/g), respectively. This approach provided new research ideas for analyzing and controlling multitarget POPs in seafood. ENVIRONMENTAL IMPLICATIONS: Persistent organic pollutants (POPs), such as perfluoroalkyl and polyfluoroalkyl substances (PFASs), polychlorinated biphenyls (PCBs), and bisphenols (BPs), have caused serious hazards to human health and ecosystems. Hence, there is a need to develop a quantitative method that can rapidly detect POPs in environmental and food samples. Herein, a novel multi-component fluorine-functionalized covalent organic skeletons (OH-F-COF) were prepared at room temperature, and served as adsorbent for POPs. The SESE-SPE strategy combined with chromatographic techniques was used to achieve a rapid detection of POPs in sea foods from the coastal provinces of China. This method provides a valuable tool for analyzing POPs in environmental and food samples.

Keywords: Covalent organic framework; Persistent organic pollutants; Sea foods; Simultaneous extraction; Solid-phase extraction; Stepwise elution.