Augmented Cardiac Inotropy by Phosphodiesterase Inhibition Requires Phosphorylation of Rad and Increased Calcium Current

Circulation. 2024 May 14;149(20):1617-1620. doi: 10.1161/CIRCULATIONAHA.123.067298. Epub 2024 May 13.
No abstract available

Keywords: calcium channels; phosphodiesterase inhibitors; phosphorylation.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Calcium / metabolism
  • Humans
  • Mice
  • Myocardial Contraction* / drug effects
  • Myocytes, Cardiac / drug effects
  • Myocytes, Cardiac / metabolism
  • Phosphodiesterase Inhibitors / pharmacology
  • Phosphodiesterase Inhibitors / therapeutic use
  • Phosphorylation

Substances

  • Phosphodiesterase Inhibitors
  • Calcium