Association between mechanical power during one-lung ventilation and pulmonary complications after thoracoscopic lung resection surgery: a prospective observational study

BMC Anesthesiol. 2024 May 17;24(1):176. doi: 10.1186/s12871-024-02562-1.

Abstract

Background: The role of mechanical power on pulmonary outcomes after thoracic surgery with one-lung ventilation was unclear. We investigated the association between mechanical power and postoperative pulmonary complications in patients undergoing thoracoscopic lung resection surgery.

Methods: In this single-center, prospective observational study, 622 patients scheduled for thoracoscopic lung resection surgery were included. Volume control mode with lung protective ventilation strategies were implemented in all participants. The primary endpoint was a composite of postoperative pulmonary complications during hospital stay. Multivariable logistic regression models were used to evaluate the association between mechanical power and outcomes.

Results: The incidence of pulmonary complications after surgery during hospital stay was 24.6% (150 of 609 patients). The multivariable analysis showed that there was no link between mechanical power and postoperative pulmonary complications.

Conclusions: In patients undergoing thoracoscopic lung resection with standardized lung-protective ventilation, no association was found between mechanical power and postoperative pulmonary complications.

Trial registration: Trial registration number: ChiCTR2200058528, date of registration: April 10, 2022.

Keywords: Mechanical power; One-lung ventilation; Postoperative pulmonary complications; Thoracic surgery.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Female
  • Humans
  • Lung Diseases / epidemiology
  • Lung Diseases / etiology
  • Male
  • Middle Aged
  • One-Lung Ventilation* / methods
  • Pneumonectomy / adverse effects
  • Pneumonectomy / methods
  • Postoperative Complications* / epidemiology
  • Postoperative Complications* / etiology
  • Prospective Studies
  • Thoracic Surgery, Video-Assisted / adverse effects
  • Thoracic Surgery, Video-Assisted / methods
  • Thoracoscopy / methods