Abstract
The authors report two clinical trials concerning chemotherapy and immunotherapy combined in the treatment of primary and metastatic brain tumors. In the first study bacillus Calmette-Guerin (BCG) and in the second Levamisole (LMS) were utilized as immunostimulating agents. Chemotherapy was performed with BCNU or CCNU in association with surgery and/or radiotherapy. The immunological response was obtained but immunotherapy failed to demonstrate any significant effect on survival.
Publication types
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Clinical Trial
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Astrocytoma / therapy
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BCG Vaccine / therapeutic use*
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Brain Neoplasms / secondary
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Brain Neoplasms / therapy*
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Breast Neoplasms / therapy
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Carmustine / therapeutic use*
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Clinical Trials as Topic
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Combined Modality Therapy
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Female
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Glioma / therapy
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Humans
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Levamisole / therapeutic use*
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Lomustine / therapeutic use*
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Lung Neoplasms / therapy
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Male
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Middle Aged
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Prognosis
Substances
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BCG Vaccine
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Levamisole
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Lomustine
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Carmustine