Histocompatibility antigens in polymyalgia rheumatica and giant cell arteritis

J Rheumatol. 1983 Aug;10(4):659-61.

Abstract

Fifty-five Caucasoid patients with polymyalgia rheumatica or giant cell arteritis were typed for HLA, A, B, C and DR locus antigens. In the total patient group, DR4 had a significantly increased frequency. The prevalence of CW3 and CW6 was also significantly increased, the rise of CW3 possibly being attributable to its well-documented linkage disequilibrium with DR4. The rise in CW6 cannot be attributed to its known linkage disequilibrium with DR7.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genes, MHC Class II*
  • Genetic Linkage
  • Giant Cell Arteritis / genetics*
  • HLA Antigens / genetics*
  • HLA-A Antigens
  • HLA-B Antigens
  • HLA-C Antigens
  • HLA-DR4 Antigen
  • HLA-DR7 Antigen
  • Histocompatibility Antigens Class II*
  • Histocompatibility Testing
  • Humans
  • Polymyalgia Rheumatica / genetics*

Substances

  • HLA Antigens
  • HLA-A Antigens
  • HLA-B Antigens
  • HLA-C Antigens
  • HLA-DR4 Antigen
  • HLA-DR7 Antigen
  • Histocompatibility Antigens Class II