Abstract
A series of 3-aryl-prop-2-enthioamide derivatives has been synthesized. These compounds were evaluated for gastro-protective activity in the rat. It has been shown that the N,N-dimethylamino derivative was the most active compound in this series [Table I comp. (II)].
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Amides / chemical synthesis*
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Animals
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Gastrointestinal Agents / chemical synthesis*
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Male
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Rats
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Rats, Inbred Strains
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Thioamides / chemical synthesis*
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Thioamides / pharmacology
Substances
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Amides
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Gastrointestinal Agents
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Thioamides