Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA

Nature. 1978 Oct 5;275(5679):416-20. doi: 10.1038/275416a0.

Abstract

The nucleosome subunits of chromatin are assembled from histones and DNA by an acidic protein which binds histones. The nucleosome assembly protein has been identified and purified from eggs of Xenopus laevis.

MeSH terms

  • Animals
  • Chromatin / ultrastructure*
  • DNA / metabolism*
  • Female
  • Histones / metabolism*
  • Hot Temperature
  • Isoelectric Point
  • Molecular Weight
  • Oocytes / physiology
  • Osmolar Concentration
  • Proteins / metabolism
  • Xenopus

Substances

  • Chromatin
  • Histones
  • Proteins
  • DNA