Induction of cytochrome P-450 in rat liver by the antibiotic troleandomycin: partial purificaton and properties of cytochrome P-450-troleandomycin metabolite complexes

Biochem Biophys Res Commun. 1981 Dec 31;103(4):1201-8. doi: 10.1016/0006-291x(81)90250-3.
No abstract available

MeSH terms

  • Animals
  • Cytochrome P-450 Enzyme System / biosynthesis*
  • Cytochrome P-450 Enzyme System / isolation & purification
  • Cytochrome P-450 Enzyme System / metabolism
  • Enzyme Induction
  • Kinetics
  • Male
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / enzymology*
  • Protein Binding
  • Rats
  • Rats, Inbred Strains
  • Spectrophotometry
  • Troleandomycin / metabolism
  • Troleandomycin / pharmacology*

Substances

  • Cytochrome P-450 Enzyme System
  • Troleandomycin