Elevation of plasma-prolactin by monoamine-oxidase inhibitors

Lancet. 1977 Aug 6;2(8032):275-6. doi: 10.1016/s0140-6736(77)90956-4.

Abstract

Plasma-prolactin levels doubled in depressive patients treated with the monoamine-oxidase inhibitors, clorgyline and pargyline. The absence of significant changes in plasma-cortisol in the same patients suggests that the increases in prolactin are not attributable to non-specific effects of stress.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Clorgyline / pharmacology*
  • Clorgyline / therapeutic use
  • Depression / drug therapy
  • Female
  • Humans
  • Hydrocortisone / blood
  • Male
  • Pargyline / pharmacology*
  • Pargyline / therapeutic use
  • Placebos
  • Prolactin / blood*
  • Propylamines / pharmacology*

Substances

  • Placebos
  • Propylamines
  • Prolactin
  • Pargyline
  • Clorgyline
  • Hydrocortisone