Decreased feeding associated with acute hypoxia in rats

Physiol Behav. 1982 Sep;29(3):455-8. doi: 10.1016/0031-9384(82)90266-9.

Abstract

Rats obtained less food than normal on a cyclic-ratio schedule during brief, 1-hr exposure to either moderate hypobaric hypoxia (BP = 435 Torr, PO2 approximately equal to 91 Torr) or to hypoxic hypoxia (BP = 750 Torr, PO2, approximately equal to 90 Torr), but not during hypobaric exposure with 36.5% oxygen (BP = 435 Torr, PO2 approximately equal to 159 Torr). The depressed rate of feeding associated with hypoxia was nevertheless well regulated. Interpreted in terms of a regulatory model, these results suggest that hypoxia suppresses eating because it degrades the taste of food, not because it impairs feeding regulation or general activity.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Altitude
  • Animals
  • Body Weight
  • Conditioning, Operant / physiology
  • Eating*
  • Female
  • Hypoxia / metabolism*
  • Models, Biological
  • Oxygen / blood
  • Rats

Substances

  • Oxygen