The experience with intraperitoneal infusion of non-absorbable steroids (triamcinolon hexacetonide) in the treatment of intractable hemodialysis-associated ascites and severe sterile peritonitis is presented. All patients uniformly responded to therapy with prolonged periods of remission and no significant complications. We conclude that intraperitoneal steroidal administration offers an effective modality of therapy in the treatment of these complications.