Class II antigens and disease susceptibility

G T Nepom

doi:10.1146/annurev.med.46.1.17

Class II antigens and disease susceptibility

Annu Rev Med. 1995:46:17-25. doi: 10.1146/annurev.med.46.1.17.

Author

G T Nepom¹

Affiliation

¹ Virginia Mason Research Center, University of Washington School of Medicine, Seattle 98101, USA.

PMID: 7598454
DOI: 10.1146/annurev.med.46.1.17

Abstract

The role for HLA typing in autoimmune disease is changing with the recognition that HLA markers can identify patients with poor prognosis in some autoimmune disease. Aggressive therapeutic intervention in patients with such HLA prognostic markers has the potential to improve or prevent progressive disease outcomes in a select group of patients.

Publication types

Review

MeSH terms

Arthritis, Rheumatoid / genetics
Arthritis, Rheumatoid / therapy
Autoimmune Diseases / genetics*
Autoimmune Diseases / therapy
Diabetes Mellitus, Type 1 / genetics
Diabetes Mellitus, Type 1 / therapy
Disease Susceptibility / therapy
Genetic Markers / genetics
Genetic Predisposition to Disease*
Histocompatibility Antigens Class II / genetics*
Humans
Prognosis
Risk Factors

Substances

Genetic Markers
Histocompatibility Antigens Class II