Nurses have many opportunities to assist individuals with schizophrenia because of the frequency and nature of their contacts. The nurses in this study believed that they can make a difference and can identify hope-instilling strategies. Strategies for rehabilitation include assisting persons with schizophrenia to set goals, seeing them as people, and joining with them on their journey of recovery. Recognizing that the establishment of the relationship is central in assisting the development of client hope, and (hopefully) eventual recovery, may help nurses to persevere despite what may be a challenging and lengthy process.