Supraglottic laryngectomy with or without postoperative radiotherapy in supraglottic carcinomas

Ann Otol Rhinol Laryngol. 1995 May;104(5):358-63. doi: 10.1177/000348949510400504.

Abstract

A retrospective review of 193 previously untreated patients with primary supraglottic carcinoma was undertaken to ascertain the efficacy of postoperative radiotherapy. All the patients received a supraglottic laryngectomy, and patients received a total of 284 elective or therapeutic neck dissections. Ninety-four (48.7%) of the patients received postoperative radiotherapy. The incidence of local recurrence was 8.2% but the recurrence rate was unrelated to the use of postoperative radiotherapy. Neck recurrence was observed in 12.9% of patients, with no influence of postoperative radiotherapy in the dissected neck. The incidence of locoregional recurrences by stage in irradiated and nonirradiated patients did not reach significant difference. The 3-year survival was 74.3%. The overall survival of the whole series and by stage was not statistically altered in combined therapy compared to surgery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Carcinoma / pathology
  • Carcinoma / radiotherapy*
  • Carcinoma / surgery*
  • Combined Modality Therapy
  • Glottis / pathology
  • Glottis / radiation effects*
  • Glottis / surgery*
  • Humans
  • Laryngeal Neoplasms / pathology
  • Laryngeal Neoplasms / radiotherapy*
  • Laryngeal Neoplasms / surgery*
  • Laryngectomy*
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Survival Rate