Non-Hodgkin's lymphoma related eosinophilic endomyocardial disease

Eur Heart J. 1994 Oct;15(10):1423-7. doi: 10.1093/oxfordjournals.eurheartj.a060406.

Abstract

Two patients with eosinophilic endomyocardial disease related to peripheral T-cell lymphomas are reported. Both patients were free of cardiac symptoms at presentation and during follow-up. Routine two dimensional echocardiography revealed bi-apical ventricular obliteration, which was also seen on MR imaging. On the T1-weighted sequence, the thickened endocardium appeared with an isointense signal. Gadolinium DOTA provided an enhanced contrast of the internal part of the left ventricular wall. On T2-weighted sequence, a thin hypointense curvilinear structure drew a dividing line between the internal, endocardial, and the external, myocardial area. Left-ventricular systolic and diastolic functions remained unaltered during subsequent follow-up.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cardiomyopathies / diagnosis
  • Cardiomyopathies / etiology*
  • Contrast Media
  • Doxorubicin / administration & dosage
  • Echocardiography
  • Echocardiography, Doppler, Pulsed
  • Endocardium / pathology
  • Epirubicin / administration & dosage
  • Heterocyclic Compounds
  • Humans
  • Hypereosinophilic Syndrome / diagnosis
  • Hypereosinophilic Syndrome / etiology*
  • Lymphoma, T-Cell, Peripheral / complications*
  • Lymphoma, T-Cell, Peripheral / drug therapy
  • Magnetic Resonance Imaging
  • Male
  • Myocardium / pathology
  • Organometallic Compounds

Substances

  • Contrast Media
  • Heterocyclic Compounds
  • Organometallic Compounds
  • Epirubicin
  • Doxorubicin
  • gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate