Abstract
The authors review 1) the pathophysiological, neuroimaging, and neurobehavioral evidence for frontal lobe involvement in closed head injury; 2) studies elucidating the cognitive deficits and behavioral disturbance related to frontal lobe lesions associated with head injury; and 3) pharmacologic treatment of the neuropsychiatric manifestations of frontal lobe injury, including emerging therapies.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Adult
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Brain Damage, Chronic / diagnosis
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Brain Damage, Chronic / physiopathology*
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Brain Damage, Chronic / psychology
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Brain Damage, Chronic / rehabilitation
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Child
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Diagnostic Imaging
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Frontal Lobe / injuries*
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Frontal Lobe / physiopathology
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Head Injuries, Closed / diagnosis
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Head Injuries, Closed / physiopathology*
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Head Injuries, Closed / psychology
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Head Injuries, Closed / rehabilitation
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Humans
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Mental Recall / physiology
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Motivation
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Neuropsychological Tests
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Problem Solving / physiology
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Psychomotor Performance / physiology
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Rehabilitation, Vocational / psychology