Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxylation of chlorzoxazone: a putative measure of CYP2E1 activity

Pharmacogenetics. 1994 Jun;4(3):162-5.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Base Sequence
  • Biotransformation
  • Carcinogens / metabolism
  • Chlorzoxazone / metabolism*
  • Cytochrome P-450 CYP2E1
  • Cytochrome P-450 Enzyme System / genetics*
  • Cytochrome P-450 Enzyme System / metabolism*
  • DNA Primers / genetics
  • Genotype
  • Humans
  • Hydroxylation
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Oxidoreductases, N-Demethylating / genetics*
  • Oxidoreductases, N-Demethylating / metabolism*
  • Polymorphism, Genetic*
  • Polymorphism, Restriction Fragment Length

Substances

  • Carcinogens
  • DNA Primers
  • Cytochrome P-450 Enzyme System
  • Cytochrome P-450 CYP2E1
  • Oxidoreductases, N-Demethylating
  • Chlorzoxazone