Cell fate determination. When is a determinant a determinant?

Curr Biol. 1994 May 1;4(5):420-2. doi: 10.1016/s0960-9822(00)00091-9.

Abstract

The Numb protein, which is asymmetrically distributed during certain cell divisions in the nervous system of Drosophila, may have a role in determining the developmental fates of the daughter cells.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Division
  • Drosophila / embryology
  • Drosophila Proteins
  • Embryonic and Fetal Development / genetics
  • Embryonic and Fetal Development / physiology*
  • Genes, Insect
  • Juvenile Hormones / genetics
  • Juvenile Hormones / physiology
  • Mutation
  • Stem Cells / cytology

Substances

  • Drosophila Proteins
  • Juvenile Hormones
  • numb protein, Drosophila