Analysis of p53 and ras gene mutations in endometriosis

Gynecol Obstet Invest. 1994;38(1):70-1. doi: 10.1159/000292450.

Abstract

No activating mutations in codons 12, 13 and 61 of ras genes nor inactivating mutations in exons 5-9 of the p53 tumor suppressor gene were detected by polymerase chain reaction and single-strand conformation polymorphism methods in either eutopic or ectopic endometrium from 10 women with severe endometriosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • DNA / analysis
  • Endometriosis / genetics*
  • Endometriosis / pathology
  • Exons
  • Female
  • Genes, p53 / genetics*
  • Humans
  • Mutation*
  • Polymerase Chain Reaction
  • Polymorphism, Single-Stranded Conformational
  • ras Proteins / analysis*
  • ras Proteins / genetics

Substances

  • DNA
  • ras Proteins