A novel polymorphism in the coding sequence of the human RET proto-oncogene

P Edery; T Attié; L M Mulligan; A Pelet; C Eng; B A Ponder; A Munnich; S Lyonnet

doi:10.1007/BF00211034

A novel polymorphism in the coding sequence of the human RET proto-oncogene

Hum Genet. 1994 Nov;94(5):579-80. doi: 10.1007/BF00211034.

Authors

P Edery¹, T Attié, L M Mulligan, A Pelet, C Eng, B A Ponder, A Munnich, S Lyonnet

Affiliation

¹ Unité de Recherches sur les Handicaps Génétiques de l'Enfant INSERM U-393, Hôpital des Enfants Malades, Paris, France.

PMID: 7959702
DOI: 10.1007/BF00211034

Abstract

A novel polymorphism in the coding sequence of the human RET proto-oncogene is described. The RET proto-oncogene maps to chromosome 10q11.2, and is involved in multiple endocrine neoplasia (MEN 2A, MEN 2B), familial medullary thyroid carcinoma and Hirschsprung's disease.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Chromosomes, Human, Pair 10
Drosophila Proteins*
Gene Frequency
Humans
Molecular Sequence Data
Polymorphism, Restriction Fragment Length*
Proto-Oncogene Mas
Proto-Oncogene Proteins / genetics*
Proto-Oncogene Proteins c-ret
Proto-Oncogenes / genetics*
Receptor Protein-Tyrosine Kinases / genetics*
White People / genetics

Substances

Drosophila Proteins
MAS1 protein, human
Proto-Oncogene Mas
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-ret
Receptor Protein-Tyrosine Kinases
Ret protein, Drosophila