Greater amount of HCV-RNA in tears compared to blood

Microbiol Immunol. 1994;38(2):157-8. doi: 10.1111/j.1348-0421.1994.tb01758.x.

Abstract

Plasma, tear fluid and swabs from eye, nose and pharynx of 33 patients were examined for presence of hepatitis C virus (HCV) RNA by polymerase chain reaction (PCR). All samples from plasma, tear fluid and eyeswabs were found to show a positive reaction in HCV-RNA PCR. Remarkably, we regularly found greater amounts of amplification products in tear fluid and eyeswabs compared to plasma using the same conditions for sample preparation.

MeSH terms

  • Base Sequence
  • Blood / microbiology*
  • Body Fluids / microbiology
  • DNA Primers / genetics
  • DNA Probes / genetics
  • Eye / microbiology
  • Hepacivirus / genetics
  • Hepacivirus / isolation & purification*
  • Hepatitis C / microbiology
  • Humans
  • Molecular Sequence Data
  • Nose / microbiology
  • Pharynx / microbiology
  • RNA, Viral / genetics
  • RNA, Viral / isolation & purification*
  • Tears / microbiology*
  • Tissue Distribution

Substances

  • DNA Primers
  • DNA Probes
  • RNA, Viral