Myocardial stunning

J Card Surg. 1994 May;9(3 Suppl):382-6. doi: 10.1111/jocs.1994.9.3s.382.

Abstract

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Myocardial stunning is an unfavorable phenomenon that is manifest during reperfusion and is caused mostly by events associated with reperfusion. This dysfunction and the accompanying contractile abnormalities delay the benefits of reperfusion therapy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Calcium / metabolism
  • Free Radicals / metabolism
  • Homeostasis
  • Humans
  • Myocardial Stunning / physiopathology*

Substances

  • Free Radicals
  • Calcium