Teniposide for meningeal carcinomatosis of small cell lung cancer

Lung Cancer. 1993 Dec;10(3-4):247-9. doi: 10.1016/0169-5002(93)90185-z.

Abstract

A female patient with small cell lung cancer and extensive bone marrow metastases achieved a complete response after combination chemotherapy including etoposide. During maintenance therapy meningeal carcinomatosis was diagnosed. After intravenous administration of teniposide she improved dramatically during 3 months.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone Marrow / pathology
  • Carboplatin / administration & dosage
  • Carcinoma, Small Cell / drug therapy
  • Carcinoma, Small Cell / secondary*
  • Carcinoma, Small Cell / therapy
  • Cyclophosphamide / administration & dosage
  • Dexamethasone / administration & dosage
  • Doxorubicin / administration & dosage
  • Etoposide / administration & dosage
  • Female
  • Humans
  • Ifosfamide / administration & dosage
  • Immunologic Factors / therapeutic use
  • Injections, Spinal
  • Interferon-gamma / therapeutic use
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / therapy
  • Meningeal Neoplasms / drug therapy
  • Meningeal Neoplasms / secondary*
  • Middle Aged
  • Morphine / administration & dosage
  • Teniposide / administration & dosage
  • Teniposide / therapeutic use*
  • Vincristine / administration & dosage

Substances

  • Immunologic Factors
  • Vincristine
  • Etoposide
  • Morphine
  • Dexamethasone
  • Doxorubicin
  • Interferon-gamma
  • Cyclophosphamide
  • Teniposide
  • Carboplatin
  • Ifosfamide