Objective: To determine the frequency of consanguineous marriages and the inbreeding coefficient in Israeli Arabs.
Design: Cohort survey.
Setting: General community in 70 settlements in Israel.
Participants: Nine thousand three hundred Israeli-Arab students in the second grade were sent questionnaires to be filled out by their fathers, with 8521 completed questionnaires returned.
Interventions: None.
Measurements/main results: Of the 8521 completed questionnaires, 1156 (14%) were from urban areas, 2267 (27%) were from suburban areas, and 5098 (60%) were from rural areas. The prevalence of consanguineous matings in the studied group was 44.3%, with a mean inbreeding coefficient of .0192. This prevalence is high and was highest in the rural areas. Marriages between first cousins occurred more often than marriages between other relatives in all locations.
Conclusion: The frequency of consanguineous marriages is quite high among Israeli Arabs, approaching 50%.