Familial cosegregation of affective disorder and Hailey-Hailey disease

Br J Psychiatry. 1993 Jul:163:109-10. doi: 10.1192/bjp.163.1.109.

Abstract

We report on a family with co-occurrence of affective disorder and Hailey-Hailey disease in two brothers and the mother. The putative chromosomal locus of Hailey-Hailey disease, which is a rare dominantly inherited dermatosis, may be a promising candidate region for genetic studies in affective disorder.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bipolar Disorder / genetics*
  • Bipolar Disorder / psychology
  • Chromosome Deletion
  • Chromosome Mapping
  • Humans
  • Male
  • Middle Aged
  • Pemphigus, Benign Familial / genetics*
  • Pemphigus, Benign Familial / psychology
  • Phenotype
  • Sex Chromosome Aberrations / genetics
  • Y Chromosome