Prolongation of allogeneic transplanted skin grafts and induction of tolerance by leflunomide, a new immunosuppressive isoxazol derivative

Transplant Proc. 1993 Feb;25(1 Pt 1):763-7.

Authors

H U Schorlemmer¹, F R Seiler, R R Bartlett

Affiliation

¹ Research Laboratories of Behringwerke AG, Marburg/Lahn, Germany.

PMID: 8438472

No abstract available

Publication types

Comparative Study

MeSH terms

Animals
Cyclosporine / therapeutic use
Drug Therapy, Combination
Graft Rejection / immunology
Graft Survival / drug effects
Graft Survival / immunology*
Immune Tolerance
Immunosuppressive Agents / therapeutic use*
Isoxazoles / therapeutic use*
Leflunomide
Lymphocytes / drug effects
Lymphocytes / immunology
Rats
Rats, Inbred BN
Rats, Inbred F344
Rats, Inbred Strains
Skin Transplantation / immunology*
Spleen / drug effects
Spleen / immunology
Time Factors
Transplantation, Homologous

Substances

Immunosuppressive Agents
Isoxazoles
Cyclosporine
Leflunomide