A recurrent chondromyxoid fibroma with chromosome aberrations ins(5;2)(q13;p21p25) and 2p deletion: a case report

Cancer Genet Cytogenet. 1993 Feb;65(2):141-6. doi: 10.1016/0165-4608(93)90223-9.

Abstract

We report a patient with a recurrent chondromyxoid fibroma, a rare benign tumor of the bone with clonal aberrations in chromosomes 2 and 5. Karyotyping, chromosome painting, interphase cytogenetics by in situ hybridization, and DNA flow cytometry were used. The karyotype was interpreted as 46,XX,der(2)ins(5;2)(q13;p21p25),der(2)ins(5;2)(q13;p21p25), der(5)ins(5;2) (q13;p21p25).

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Bone Neoplasms / genetics*
  • Bone Neoplasms / surgery
  • Chondroma / genetics*
  • Chondroma / surgery
  • Chromosomes, Human, Pair 1
  • Chromosomes, Human, Pair 12
  • Chromosomes, Human, Pair 2*
  • Chromosomes, Human, Pair 5*
  • Chromosomes, Human, Pair 7
  • DNA, Neoplasm / analysis
  • Female
  • Humans
  • Karyotyping
  • Neoplasm Recurrence, Local / genetics*
  • Neoplasm Recurrence, Local / surgery
  • Radius* / surgery
  • Reoperation
  • Translocation, Genetic / genetics*
  • Trisomy

Substances

  • DNA, Neoplasm