Intracardiac injection of T-61, a veterinary euthanasia drug

P Hantson; C Semaan; J C Jouret; J Rahier; R Lauwerys; J P Brunain; P Mahieu

doi:10.3109/15563659609013777

Intracardiac injection of T-61, a veterinary euthanasia drug

J Toxicol Clin Toxicol. 1996;34(2):235-9. doi: 10.3109/15563659609013777.

Authors

P Hantson¹, C Semaan, J C Jouret, J Rahier, R Lauwerys, J P Brunain, P Mahieu

Affiliation

¹ Cliniques Universitaires St-Luc, Brussels, Belgium.

PMID: 8618261
DOI: 10.3109/15563659609013777

Abstract

We report a suicidal attempt by intracardiac injection of T-61, a veterinary euthanasia drug containing embutramide, mebezonium and tetracaine in dimethylformamide. The main complications were reversible acute renal failure and pericardial effusion. There was a delayed abnormality of the liver function tests possibly related to the dimethylformamide solvent. A liver biopsy on day 16 showed a normal hepatic architecture with lipid-containing lysosomes and prominent vesicular endoplasmic reticulum noted on electron microscopy.

Publication types

Case Reports

MeSH terms

Acute Kidney Injury / chemically induced
Adult
Amides / administration & dosage
Amides / poisoning*
Drug Combinations
Endoplasmic Reticulum, Rough / drug effects
Endoplasmic Reticulum, Rough / ultrastructure
Humans
Injections
Liver / drug effects
Liver / pathology
Liver / ultrastructure
Liver Function Tests
Lysosomes / drug effects
Lysosomes / ultrastructure
Pericardial Effusion / chemically induced
Quaternary Ammonium Compounds / administration & dosage
Quaternary Ammonium Compounds / poisoning*
Suicide, Attempted*
Tetracaine / administration & dosage
Tetracaine / poisoning*
Time Factors

Substances

Amides
Drug Combinations
Quaternary Ammonium Compounds
Tetracaine
T 61