Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients

Biol Psychiatry. 1997 May 1;41(9):955-63. doi: 10.1016/S0006-3223(97)89928-3.

Abstract

Light is known to be an important modulator of circadian rhythms. We tested the hypothesis than an enduring increase in the daytime environmental illumination level improves rest-activity rhythm disturbances in demented patients. Actigraphy was performed before, during, and after 4 weeks of increased illumination in the living rooms of 22 patients with dementia clinically diagnosed as probable Alzheimer's disease, multi-infarct dementia, dementia associated with alcoholism, or normal pressure hydrocephalus. The results indicated that during increased illumination, the stability of the rest-activity rhythm increased in patients with intact vision, but not in visually impaired patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alcoholism / complications
  • Alzheimer Disease / therapy*
  • Circadian Rhythm*
  • Dementia / therapy*
  • Dementia, Multi-Infarct / therapy
  • Female
  • Geriatric Assessment
  • Humans
  • Hydrocephalus, Normal Pressure / complications
  • Male
  • Middle Aged
  • Phototherapy*
  • Sleep*
  • Social Environment
  • Treatment Outcome
  • Wakefulness*