Adrenal cortical response to circumcision in the neonate

Obstet Gynecol. 1976 Aug;48(2):208-10.

Abstract

A study was designed to document the responsiveness of the hypothalamic-pituitary-adrenal axis to the stress of circumcision during the first 6 hours of life. There was a rise in both serum cortisol and cortisone levels in all infants studied. The rise in cortisol was greater than the rise in cortisone in all infants.

MeSH terms

  • Circumcision, Male*
  • Cortisone / blood*
  • Female
  • Fetal Distress / physiopathology
  • Humans
  • Hydrocortisone / blood*
  • Infant, Newborn
  • Male
  • Pituitary-Adrenal System / physiopathology
  • Pregnancy
  • Respiratory Distress Syndrome, Newborn / physiopathology
  • Stress, Physiological / blood*

Substances

  • Cortisone
  • Hydrocortisone