Oral delivery of heparin in combination with sodium N-[8-(2-hydroxybenzoyl)amino]caprylate: pharmacological considerations

Pharm Res. 1997 Dec;14(12):1830-4. doi: 10.1023/a:1012160703533.

Authors

T M Rivera¹, A Leone-Bay, D R Paton, H R Leipold, R A Baughman

Affiliation

¹ Emisphere Technologies, Inc., Hawthorne, New York 10532, USA.

PMID: 9453076
DOI: 10.1023/a:1012160703533

No abstract available

MeSH terms

Administration, Oral
Animals
Caprylates / metabolism
Caprylates / pharmacology*
Drug Combinations
Duodenum / cytology
Duodenum / drug effects
Female
Heparin / administration & dosage
Heparin / pharmacokinetics*
Ileum / cytology
Ileum / drug effects
Intestinal Absorption / drug effects*
Jejunum / cytology
Jejunum / drug effects
Macaca fascicularis
Male
Partial Thromboplastin Time
Rats
Rats, Sprague-Dawley
Stomach / cytology
Stomach / drug effects

Substances

Caprylates
Drug Combinations
N-(8-(2-hydroxybenzoyl)amino)caprylate
Heparin