Cytogenetics of an atypical Spitz nevus metastatic to a single lymph node

N M Smith; M J Evans; A Pearce; W H Wallace

Cytogenetics of an atypical Spitz nevus metastatic to a single lymph node

Pediatr Pathol Lab Med. 1998 Jan-Feb;18(1):115-22.

Authors

N M Smith¹, M J Evans, A Pearce, W H Wallace

Affiliation

¹ Department of Paediatric Pathology, Royal Hospital for Sick Children, Edinburgh, United Kingdom.

PMID: 9566288

Abstract

Clinicopathologic details of an atypical Spitz nevus are reported. A metastasis to a single ipsilateral lymph node is documented. Cytogenetic analysis of the metastatic lesion revealed a clonal chromosomal abnormality, add(6)(q12-13), previously noted in cases of malignant melanoma.

Publication types

Case Reports

MeSH terms

Chromosome Aberrations
Chromosomes, Human, Pair 6
Female
Humans
Infant
Lymphatic Metastasis
Melanoma / genetics
Nevus, Epithelioid and Spindle Cell / genetics
Nevus, Epithelioid and Spindle Cell / pathology*
Skin Neoplasms / genetics
Skin Neoplasms / pathology*