Variant in the regulatory subunit of phosphatidylinositol 3-kinase (p85alpha): preliminary evidence indicates a potential role of this variant in the acute insulin response and type 2 diabetes in Pima women

Diabetes. 1998 Jun;47(6):973-5. doi: 10.2337/diabetes.47.6.973.

Authors

L J Baier¹, C Wiedrich, R L Hanson, C Bogardus

Affiliation

¹ Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016, USA. lbaier@phx.niddk.nih.gov

PMID: 9604878
DOI: 10.2337/diabetes.47.6.973

No abstract available

MeSH terms

Adult
Arizona
Blood Glucose / drug effects
Blood Glucose / metabolism
Diabetes Mellitus, Type 2 / enzymology*
Diabetes Mellitus, Type 2 / epidemiology
Diabetes Mellitus, Type 2 / genetics*
Female
Genetic Variation*
Genotype
Glucose / metabolism
Glucose Tolerance Test
Humans
Indians, North American / genetics*
Insulin / blood
Insulin / pharmacology*
Insulin Resistance / genetics*
Macromolecular Substances
Phosphatidylinositol 3-Kinases / chemistry
Phosphatidylinositol 3-Kinases / genetics*
Point Mutation*
Polymorphism, Genetic
Prevalence

Substances

Blood Glucose
Insulin
Macromolecular Substances
Phosphatidylinositol 3-Kinases
Glucose