Abstract
In the yeast Saccharomyces cerevisiae, heterochromatin-like regions are formed at the silent mating type loci and at telomeres. The past year of investigations has led to a clearer understanding of the nature of nucleation and spreading of heterochromatin, as well as uncovering a fascinating link between silencing, the nucleolus and aging.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Animals
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Cell Nucleolus
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Chromatin
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DNA Repair
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DNA Replication
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Fungal Proteins / metabolism
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Gene Expression Regulation, Fungal*
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Humans
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Ligands
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Saccharomyces cerevisiae / genetics*
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Silent Information Regulator Proteins, Saccharomyces cerevisiae*
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Telomere
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Ubiquitins / metabolism
Substances
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Chromatin
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Fungal Proteins
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Ligands
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SIR4 protein, S cerevisiae
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Silent Information Regulator Proteins, Saccharomyces cerevisiae
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Ubiquitins