[Immunomorphological characteristics of primary and recurrent breast neoplasms]

N N Volchenko; L E Zavalishina; I B Shimbireva; G A Frank

[Immunomorphological characteristics of primary and recurrent breast neoplasms]

Arkh Patol. 1998 Jul-Aug;60(4):4-7.

[Article in Russian]

Authors

N N Volchenko¹, L E Zavalishina, I B Shimbireva, G A Frank

Affiliation

¹ P. A. Herzen Moscow Oncological Institute, Moscow.

PMID: 9791688

Abstract

Primary and recurring breast carcinomas do not differ in the expression of proliferating cell nuclear antigen (PCNA), C-erb-2 oncoprotein, carcinoembryonic antigen and trophoblastic antigen. The content of PCNA and C-erb-2 oncoprotein is twice as high in tumors with an unfavorable prognosis and the frequency of combination of these markers is much higher comparing to tumors with a good prognosis.

Publication types

English Abstract

MeSH terms

Biomarkers, Tumor*
Breast Neoplasms / metabolism*
Breast Neoplasms / pathology*
Carcinoembryonic Antigen / analysis*
Carcinoembryonic Antigen / metabolism
Female
Humans
Immunohistochemistry
Proliferating Cell Nuclear Antigen / analysis*
Proliferating Cell Nuclear Antigen / metabolism
Receptor, ErbB-2 / analysis*
Receptor, ErbB-2 / metabolism
Recurrence

Substances

Biomarkers, Tumor
Carcinoembryonic Antigen
Proliferating Cell Nuclear Antigen
Receptor, ErbB-2