Efficacies were studied of enterosorbents (ES) and antioxidants (AO) combined in treatment of chronic hepatic pathology of alcoholic etiology. 102 patients were given ES (enterosgel, polysorb, sillard) in combination with tocopheroli acetas over 6 to 10 days. The control group comprised 84 individuals. A positive effect was ascertained of an ES + AO combination on the clinical course of the illness and on the immunological indices, which observation warrants the above drugs to be included into a combined treatment of patients presenting with chronic disorders of the liver of alcoholic etiology.