Bisamides, lignans, triterpenes, and insecticidal Cyclopenta[b]benzofurans from Aglaia species

J Nat Prod. 1998 Dec;61(12):1482-90. doi: 10.1021/np9801965.

Abstract

Twelve new derivatives of bisamides [piriferinol (5), edulimide (7)], lignans [lariciresinol acetat (10)], triterpenes [4-bis-norcycloartane-type triterpenes (11a, 12a+b, 13a+b)], cyclopenta[b]benzofurans [pannellin (15), pannellin 1-O-acetate (16), 3'-methoxypannellin (17)], and an aromatic butyrolactone [aglalactone (18)] were isolated and identified from lipophilic leaf, stem, and root extracts of Aglaia spp. elaeagnoidea, edulis, grandis, silvestris, and tomentosa. Two cyclopenta[b]benzofurans (flavaglines), pannellin (15) and pannellin 1-O-acetate (16), displayed very strong insecticidal activity against Spodoptera littoralis and Lymantria dispar, comparable with the activity of azadirachtin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Benzofurans / isolation & purification
  • Benzofurans / toxicity*
  • Chromatography, High Pressure Liquid
  • Insecta
  • Insecticides / isolation & purification
  • Insecticides / toxicity*
  • Larva
  • Plant Leaves / chemistry
  • Plants / chemistry*
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet
  • Spodoptera

Substances

  • Benzofurans
  • Insecticides