Abstract
This case report details a single patient with pure red cell aplasia (PRCA) associated with clonal CD3+, TCRalphabeta+, TCR-Vbeta8+, CD8+, CD57+ large granular lymphocytosis whose anaemia did not respond to conventional immunosuppressive therapy but did respond to cyclosporin A (CsA). The patient has become dependent on CsA for 7 years in order to control anaemia due to associated PRCA.
MeSH terms
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Aged
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CD8-Positive T-Lymphocytes / pathology*
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Cell Size
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Clone Cells
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Cyclosporine / therapeutic use
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Cytoplasmic Granules
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Humans
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Immunosuppressive Agents / therapeutic use
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Lymphocytosis / complications*
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Lymphocytosis / pathology*
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Male
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Middle Aged
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Red-Cell Aplasia, Pure / complications*
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Red-Cell Aplasia, Pure / drug therapy
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Substance-Related Disorders / blood
Substances
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Immunosuppressive Agents
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Cyclosporine