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Activation of signaling pathways in models of t(6;9)-acute myeloid leukemia.
Ann Hematol. 2022 Oct;101(10):2179-2193. doi: 10.1007/s00277-022-04905-9. Epub 2022 Aug 8.
Ann Hematol. 2022.
PMID: 35941390
Free PMC article.
Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1T315I and BCR-ABL1T315I-E255K.
Mian AA, Haberbosch I, Khamaisie H, Agbarya A, Pietsch L, Eshel E, Najib D, Chiriches C, Ottmann OG, Hantschel O, Biondi RM, Ruthardt M, Mahajna J.
Mian AA, et al. Among authors: chiriches c.
Ann Hematol. 2021 Aug;100(8):2023-2029. doi: 10.1007/s00277-020-04357-z. Epub 2021 Jun 10.
Ann Hematol. 2021.
PMID: 34110462
Free PMC article.
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Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation.
Chiriches C, Nicolaisen N, Wieske M, Elhaddad H, Mehmetbeyoglu E, Alvares C, Becher D, Hole P, Ottmann OG, Ruthardt M.
Chiriches C, et al.
PLoS Genet. 2022 Oct 26;18(10):e1010463. doi: 10.1371/journal.pgen.1010463. eCollection 2022 Oct.
PLoS Genet. 2022.
PMID: 36288392
Free PMC article.
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