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First-in-Class Phosphorylated-p68 Inhibitor RX-5902 Inhibits β-Catenin Signaling and Demonstrates Antitumor Activity in Triple-Negative Breast Cancer.
Capasso A, Bagby SM, Dailey KL, Currimjee N, Yacob BW, Ionkina A, Frank JG, Kim DJ, George C, Lee YB, Benaim E, Gittleman B, Hartman SJ, Tan AC, Kim J, Pitts TM, Eckhardt SG, Tentler JJ, Diamond JR. Capasso A, et al. Mol Cancer Ther. 2019 Nov;18(11):1916-1925. doi: 10.1158/1535-7163.MCT-18-1334. Epub 2019 Sep 5. Mol Cancer Ther. 2019. PMID: 31488700 Free PMC article.
Efficacy and Molecular Mechanisms of Differentiated Response to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Models of p53-Mutated Triple-Negative Breast Cancer.
Ionkina AA, Tentler JJ, Kim J, Capasso A, Pitts TM, Ryall KA, Howison RR, Kabos P, Sartorius CA, Tan AC, Eckhardt SG, Diamond JR. Ionkina AA, et al. Front Oncol. 2017 May 15;7:94. doi: 10.3389/fonc.2017.00094. eCollection 2017. Front Oncol. 2017. PMID: 28555173 Free PMC article.
Preclinical and Dose-Finding Phase I Trial Results of Combined Treatment with a TORC1/2 Inhibitor (TAK-228) and Aurora A Kinase Inhibitor (Alisertib) in Solid Tumors.
Davis SL, Ionkina AA, Bagby SM, Orth JD, Gittleman B, Marcus JM, Lam ET, Corr BR, O'Bryant CL, Glode AE, Tan AC, Kim J, Tentler JJ, Capasso A, Lopez KL, Gustafson DL, Messersmith WA, Leong S, Eckhardt SG, Pitts TM, Diamond JR. Davis SL, et al. Among authors: ionkina aa. Clin Cancer Res. 2020 Sep 1;26(17):4633-4642. doi: 10.1158/1078-0432.CCR-19-3498. Epub 2020 May 15. Clin Cancer Res. 2020. PMID: 32414750 Free PMC article. Clinical Trial.
Rapid Multicomponent Bioluminescence Imaging via Substrate Unmixing.
Rathbun CM, Ionkina AA, Yao Z, Jones KA, Porterfield WB, Prescher JA. Rathbun CM, et al. Among authors: ionkina aa. ACS Chem Biol. 2021 Apr 16;16(4):682-690. doi: 10.1021/acschembio.0c00959. Epub 2021 Mar 17. ACS Chem Biol. 2021. PMID: 33729750 Free PMC article.
Multiplexed bioluminescence imaging with a substrate unmixing platform.
Brennan CK, Yao Z, Ionkina AA, Rathbun CM, Sathishkumar B, Prescher JA. Brennan CK, et al. Among authors: ionkina aa. Cell Chem Biol. 2022 Nov 17;29(11):1649-1660.e4. doi: 10.1016/j.chembiol.2022.10.004. Epub 2022 Oct 24. Cell Chem Biol. 2022. PMID: 36283402 Free PMC article.