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SDF1α-induced chemotaxis of JAK2-V617F-positive cells is dependent on Bruton tyrosine kinase and its downstream targets PI3K/AKT, PLCγ1 and RhoA.
Nimmagadda SC, Frey S, Müller P, Wolleschak D, Weinert S, Keller U, Edelmann B, Fischer T. Nimmagadda SC, et al. Among authors: edelmann b. Haematologica. 2019 Jul;104(7):e288-e292. doi: 10.3324/haematol.2018.201921. Epub 2019 Feb 14. Haematologica. 2019. PMID: 30765477 Free PMC article. No abstract available.
JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.
Edelmann B, Gupta N, Schnoeder TM, Oelschlegel AM, Shahzad K, Goldschmidt J, Philipsen L, Weinert S, Ghosh A, Saalfeld FC, Nimmagadda SC, Müller P, Braun-Dullaeus R, Mohr J, Wolleschak D, Kliche S, Amthauer H, Heidel FH, Schraven B, Isermann B, Müller AJ, Fischer T. Edelmann B, et al. J Clin Invest. 2018 Oct 1;128(10):4359-4371. doi: 10.1172/JCI90312. Epub 2018 Jul 19. J Clin Invest. 2018. PMID: 30024857 Free PMC article.
Comparative Assessment of Female Mouse Model of Graves' Orbitopathy Under Different Environments, Accompanied by Proinflammatory Cytokine and T-Cell Responses to Thyrotropin Hormone Receptor Antigen.
Berchner-Pfannschmidt U, Moshkelgosha S, Diaz-Cano S, Edelmann B, Görtz GE, Horstmann M, Noble A, Hansen W, Eckstein A, Banga JP. Berchner-Pfannschmidt U, et al. Among authors: edelmann b. Endocrinology. 2016 Apr;157(4):1673-82. doi: 10.1210/en.2015-1829. Epub 2016 Feb 12. Endocrinology. 2016. PMID: 26872090
34 results