Harris PWR - Search Results

1

Genome mining, isolation, chemical synthesis and biological evaluation of a novel lanthipeptide, tikitericin, from the extremophilic microorganism Thermogemmatispora strain T81.

Xu B, Aitken EJ, Baker BP, Turner CA, Harvey JE, Stott MB, Power JF, Harris PWR, Keyzers RA, Brimble MA. Xu B, et al. Among authors: harris pwr. Chem Sci. 2018 Aug 20;9(37):7311-7317. doi: 10.1039/c8sc02170h. eCollection 2018 Oct 7. Chem Sci. 2018. PMID: 30294420 Free PMC article.

2

Synthesis of cyclic proline-containing peptides via ring-closing metathesis.

Harris PW, Brimble MA, Gluckman PD. Harris PW, et al. Org Lett. 2003 May 29;5(11):1847-50. doi: 10.1021/ol034370e. Org Lett. 2003. PMID: 12762668

3

Synthesis and neuroprotective activity of analogues of glycyl-L-prolyl-L-glutamic acid (GPE) modified at the alpha-carboxylic acid.

Trotter NS, Brimble MA, Harris PW, Callis DJ, Sieg F. Trotter NS, et al. Bioorg Med Chem. 2005 Jan 17;13(2):501-17. doi: 10.1016/j.bmc.2004.10.005. Bioorg Med Chem. 2005. PMID: 15598572

4

Synthesis and pharmacological evaluation of side chain modified glutamic acid analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE).

Brimble MA, Trotter NS, Harris PW, Sieg F. Brimble MA, et al. Bioorg Med Chem. 2005 Jan 17;13(2):519-32. doi: 10.1016/j.bmc.2004.10.006. Bioorg Med Chem. 2005. PMID: 15598573

5

Synthesis and pharmacological evaluation of glycine-modified analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE).

Lai MY, Brimble MA, Callis DJ, Harris PW, Levi MS, Sieg F. Lai MY, et al. Bioorg Med Chem. 2005 Jan 17;13(2):533-48. doi: 10.1016/j.bmc.2004.10.004. Bioorg Med Chem. 2005. PMID: 15598574

6

Synthesis of macrocyclic analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE).

Harris PW, Brimble MA. Harris PW, et al. Org Biomol Chem. 2006 Jul 21;4(14):2696-709. doi: 10.1039/b605293b. Epub 2006 Jun 1. Org Biomol Chem. 2006. PMID: 16826294

7

Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia-ischemia in adult rats.

Guan J, Mathai S, Harris P, Wen JY, Zhang R, Brimble M, Gluckman P. Guan J, et al. Neuropharmacology. 2007 Nov;53(6):749-62. doi: 10.1016/j.neuropharm.2007.08.010. Epub 2007 Aug 19. Neuropharmacology. 2007. PMID: 17904590

8

Synthesis of fluorescein-labelled O-mannosylated peptides as components for synthetic vaccines: comparison of two synthetic strategies.

Brimble MA, Kowalczyk R, Harris PW, Dunbar PR, Muir VJ. Brimble MA, et al. Org Biomol Chem. 2008 Jan 7;6(1):112-21. doi: 10.1039/b712926b. Epub 2007 Oct 26. Org Biomol Chem. 2008. PMID: 18075655

9

NNZ-2566: a Gly-Pro-Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke.

Bickerdike MJ, Thomas GB, Batchelor DC, Sirimanne ES, Leong W, Lin H, Sieg F, Wen J, Brimble MA, Harris PW, Gluckman PD. Bickerdike MJ, et al. J Neurol Sci. 2009 Mar 15;278(1-2):85-90. doi: 10.1016/j.jns.2008.12.003. Epub 2009 Jan 20. J Neurol Sci. 2009. PMID: 19157421

10

A one-pot approach to neoglycopeptides using orthogonal native chemical ligation and click chemistry.

Lee DJ, Mandal K, Harris PW, Brimble MA, Kent SB. Lee DJ, et al. Org Lett. 2009 Nov 19;11(22):5270-3. doi: 10.1021/ol902131n. Org Lett. 2009. PMID: 19842689

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