Shimizu H - Search Results

1

Visualization of Modified Bisarylbutadiyne-Tagged Small Molecules in Live-Cell Nuclei by Stimulated Raman Scattering Microscopy.

Kawaguchi M, Yonetani Y, Mizuguchi T, Spratt SJ, Asanuma M, Shimizu H, Sasaki M, Ozeki Y. Kawaguchi M, et al. Among authors: shimizu h. Anal Chem. 2024 Apr 30;96(17):6643-6651. doi: 10.1021/acs.analchem.3c05946. Epub 2024 Apr 16. Anal Chem. 2024. PMID: 38626411

2

Target identification of hepcidin production inhibitors by a combination of chemical proteomics and radioactive compound binding assay.

Sasaki M, Ueda K, Fukuda T, Tanaka N, Shimizu H, Kubota K. Sasaki M, et al. Among authors: shimizu h. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2878-2884. doi: 10.1016/j.bbrc.2018.08.061. Epub 2018 Aug 21. Biochem Biophys Res Commun. 2018. PMID: 30139518

3

Perturbation-Based Proteomic Correlation Profiling as a Target Deconvolution Methodology.

Ohki Y, Sakurai H, Hoshino M, Terashima H, Shimizu H, Ishikawa T, Ogiyama T, Muramatsu Y, Nakanishi T, Miyazaki S, Tsuruoka H, Kobayashi H, Kubota K. Ohki Y, et al. Among authors: shimizu h. Cell Chem Biol. 2019 Jan 17;26(1):137-143.e8. doi: 10.1016/j.chembiol.2018.10.012. Epub 2018 Nov 15. Cell Chem Biol. 2019. PMID: 30449674 Free article.

4

Discovery of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors with Antitumor Activity.

Taniguchi T, Inagaki H, Baba D, Yasumatsu I, Toyota A, Kaneta Y, Kiga M, Iimura S, Odagiri T, Shibata Y, Ueda K, Seo M, Shimizu H, Imaoka T, Nakayama K. Taniguchi T, et al. Among authors: shimizu h. ACS Med Chem Lett. 2019 Mar 15;10(5):737-742. doi: 10.1021/acsmedchemlett.8b00631. eCollection 2019 May 9. ACS Med Chem Lett. 2019. PMID: 31097992 Free PMC article.

5

Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 3: exploration of effective compounds in arthritis models.

Shimizu H, Yamasaki T, Yoneda Y, Muro F, Hamada T, Yasukochi T, Tanaka S, Toki T, Yokoyama M, Morishita K, Iimura S. Shimizu H, et al. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4550-5. doi: 10.1016/j.bmcl.2011.05.115. Epub 2011 Jun 6. Bioorg Med Chem Lett. 2011. PMID: 21705219

6

Systematic Exploration of Passive Permeability in Tetrapeptides with Hydrogen-Bond-Accepting Amino Acid Side Chains.

Shimizu H, Renslo AR. Shimizu H, et al. ChemMedChem. 2022 Aug 17;17(16):e202200204. doi: 10.1002/cmdc.202200204. Epub 2022 Jul 8. ChemMedChem. 2022. PMID: 35696654

7

Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: improvement of potency in vitro and in vivo.

Shimizu H, Yasumatsu I, Hamada T, Yoneda Y, Yamasaki T, Tanaka S, Toki T, Yokoyama M, Morishita K, Iimura S. Shimizu H, et al. Bioorg Med Chem Lett. 2011 Feb 1;21(3):904-8. doi: 10.1016/j.bmcl.2010.12.078. Epub 2010 Dec 21. Bioorg Med Chem Lett. 2011. PMID: 21232950

8

Discovery of imidazo[1,2-b]pyridazine derivatives as IKKbeta inhibitors. Part 1: Hit-to-lead study and structure-activity relationship.

Shimizu H, Tanaka S, Toki T, Yasumatsu I, Akimoto T, Morishita K, Yamasaki T, Yasukochi T, Iimura S. Shimizu H, et al. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5113-8. doi: 10.1016/j.bmcl.2010.07.026. Epub 2010 Jul 13. Bioorg Med Chem Lett. 2010. PMID: 20675134

9

A novel inhibitor of I-kappaB kinase beta ameliorates experimental arthritis through downregulation of proinflammatory cytokines in arthritic joints.

Tanaka S, Toki T, Yokoyama M, Shimizu H, Yamasaki T, Yoneda Y, Muro F, Yasukochi T, Iimura S, Morishita K. Tanaka S, et al. Among authors: shimizu h. Biol Pharm Bull. 2014;37(1):87-95. doi: 10.1248/bpb.b13-00628. Biol Pharm Bull. 2014. PMID: 24389485 Free article.

10

A Randomized Trial of Ionic Silver Dressing to Reduce Surgical Site Infection After Gastrointestinal Surgery.

Kosugi C, Koda K, Shimizu H, Yamazaki M, Shuto K, Mori M, Usui A, Nojima H, Endo S, Yanagibashi H, Arimitsu H, Tochigi T, Sazuka T, Hirota M, Kuboki H. Kosugi C, et al. Among authors: shimizu h. Ann Surg Open. 2024 Mar 14;5(1):e402. doi: 10.1097/AS9.0000000000000402. eCollection 2024 Mar. Ann Surg Open. 2024. PMID: 38883952 Free PMC article.

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