Allegra CJ - Search Results

1

Polyglutamation of methotrexate. Is methotrexate a prodrug?

Chabner BA, Allegra CJ, Curt GA, Clendeninn NJ, Baram J, Koizumi S, Drake JC, Jolivet J. Chabner BA, et al. Among authors: allegra cj. J Clin Invest. 1985 Sep;76(3):907-12. doi: 10.1172/JCI112088. J Clin Invest. 1985. PMID: 2413074 Free PMC article. Review. No abstract available.

2

Effect of methotrexate on intracellular folate pools in purified myeloid precursor cells from normal human bone marrow.

Baram J, Allegra CJ, Fine RL, Chabner BA. Baram J, et al. Among authors: allegra cj. J Clin Invest. 1987 Mar;79(3):692-7. doi: 10.1172/JCI112872. J Clin Invest. 1987. PMID: 3818945 Free PMC article.

3

Enzyme studies of methotrexate-resistant human leukemic cell (K562) subclones.

Koizumi S, Allegra CJ. Koizumi S, et al. Among authors: allegra cj. Leuk Res. 1992 Jun-Jul;16(6-7):565-9. doi: 10.1016/0145-2126(92)90003-p. Leuk Res. 1992. PMID: 1378915

4

Mechanism of thymidylate synthase inhibition by methotrexate in human neoplastic cell lines and normal human myeloid progenitor cells.

Chu E, Drake JC, Boarman D, Baram J, Allegra CJ. Chu E, et al. Among authors: allegra cj. J Biol Chem. 1990 May 25;265(15):8470-8. J Biol Chem. 1990. PMID: 2341391 Free article.

5

Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.

Allegra CJ, Chabner BA, Drake JC, Lutz R, Rodbard D, Jolivet J. Allegra CJ, et al. J Biol Chem. 1985 Aug 15;260(17):9720-6. J Biol Chem. 1985. PMID: 2410416 Free article.

6

Effects on dihydrofolate reductase of methotrexate metabolites and intracellular folates formed following methotrexate exposure of human breast cancer cells.

Drake JC, Allegra CJ, Baram J, Kaufman BT, Chabner BA. Drake JC, et al. Among authors: allegra cj. Biochem Pharmacol. 1987 Jul 15;36(14):2416-8. doi: 10.1016/0006-2952(87)90612-5. Biochem Pharmacol. 1987. PMID: 2440441 No abstract available.

7

Potent in vitro and in vivo antitoxoplasma activity of the lipid-soluble antifolate trimetrexate.

Allegra CJ, Kovacs JA, Drake JC, Swan JC, Chabner BA, Masur H. Allegra CJ, et al. J Clin Invest. 1987 Feb;79(2):478-82. doi: 10.1172/JCI112837. J Clin Invest. 1987. PMID: 2948969 Free PMC article.

8

Measuring levels of methotrexate.

Allegra CJ, Drake JC, Bell BA, Curt GA, Chabner BA. Allegra CJ, et al. N Engl J Med. 1985 Jul 18;313(3):184. doi: 10.1056/nejm198507183130316. N Engl J Med. 1985. PMID: 3892295 No abstract available.

9

A re-evaluation of the competitive protein binding assay for methotrexate binding to dihydrofolate reductase.

Drake JC, Allegra CJ, Chabner BA. Drake JC, et al. Among authors: allegra cj. Biochem Pharmacol. 1986 Apr 1;35(7):1212-4. doi: 10.1016/0006-2952(86)90166-8. Biochem Pharmacol. 1986. PMID: 3964298 No abstract available.

10

Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.

Allegra CJ, Drake JC, Jolivet J, Chabner BA. Allegra CJ, et al. Proc Natl Acad Sci U S A. 1985 Aug;82(15):4881-5. doi: 10.1073/pnas.82.15.4881. Proc Natl Acad Sci U S A. 1985. PMID: 3860829 Free PMC article.

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