Stalk segment 5 of the yeast plasma membrane H(+)-ATPase. Labeling with a fluorescent maleimide reveals a conformational change during glucose activation.
Miranda M, Pardo JP, Allen KE, Slayman CW.
Miranda M, et al.
J Biol Chem. 2002 Oct 25;277(43):40981-8. doi: 10.1074/jbc.M206793200. Epub 2002 Aug 6.
J Biol Chem. 2002.
PMID: 12169695
Free article.
Recent mutagenesis studies have shown that glucose-dependent activation can be mimicked constitutively by amino acid substitutions in stalk segment 5 (S5), an alpha-helical stretch connecting the catalytic part of the ATPase with transmembrane segment 5 (Miranda, M., Allen …
Recent mutagenesis studies have shown that glucose-dependent activation can be mimicked constitutively by amino acid substitutions in stalk …