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Page 1
Targeting KRAS in cancer.
Singhal A, Li BT, O'Reilly EM. Singhal A, et al. Nat Med. 2024 Apr;30(4):969-983. doi: 10.1038/s41591-024-02903-0. Epub 2024 Apr 18. Nat Med. 2024. PMID: 38637634 Review.
Alveolar Differentiation Drives Resistance to KRAS Inhibition in Lung Adenocarcinoma.
Li Z, Zhuang X, Pan CH, Yan Y, Thummalapalli R, Hallin J, Torborg S, Singhal A, Chang JC, Manchado E, Dow LE, Yaeger R, Christensen JG, Lowe SW, Rudin CM, Joost S, Tammela T. Li Z, et al. Among authors: singhal a. Cancer Discov. 2024 Feb 8;14(2):308-325. doi: 10.1158/2159-8290.CD-23-0289. Cancer Discov. 2024. PMID: 37931288
Systematic Comparison of Pancreatic Ductal Adenocarcinoma Models Identifies a Conserved Highly Plastic Basal Cell State.
Pitter KL, Grbovic-Huezo O, Joost S, Singhal A, Blum M, Wu K, Holm M, Ferrena A, Bhutkar A, Hudson A, Lecomte N, de Stanchina E, Chaligne R, Iacobuzio-Donahue CA, Pe'er D, Tammela T. Pitter KL, et al. Among authors: singhal a. Cancer Res. 2022 Oct 4;82(19):3549-3560. doi: 10.1158/0008-5472.CAN-22-1742. Cancer Res. 2022. PMID: 35952360 Free PMC article.
Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma.
Li Z, Zhuang X, Pan CH, Yan Y, Thummalapalli R, Hallin J, Torborg S, Singhal A, Chang JC, Manchado E, Dow LE, Yaeger R, Christensen JG, Lowe SW, Rudin CM, Joost S, Tammela T. Li Z, et al. Among authors: singhal a. bioRxiv [Preprint]. 2023 Oct 1:2023.09.29.560194. doi: 10.1101/2023.09.29.560194. bioRxiv. 2023. PMID: 37808711 Free PMC article. Updated. Preprint.
Solid tumor growth depends on an intricate equilibrium of malignant cell states.
Torborg SR, Grbovic-Huezo O, Singhal A, Holm M, Wu K, Han X, Ho YJ, Haglund C, Mitchell MJ, Lowe SW, Dow LE, Pitter KL, Sanchez-Rivera FJ, Levchenko A, Tammela T. Torborg SR, et al. Among authors: singhal a. bioRxiv [Preprint]. 2023 Dec 30:2023.12.30.573100. doi: 10.1101/2023.12.30.573100. bioRxiv. 2023. PMID: 38234855 Free PMC article. Preprint.
Precision medicine for pancreatic cancer: Characterizing the clinico-genomic landscape and outcomes of KRAS G12C-mutated disease.
Keane F, Chou JF, Walch H, Schoenfeld J, Singhal A, Cowzer D, Harrold E, O'Connor C, Park W, Varghese A, El Dika I, Balogun F, Yu KH, Capanu M, Schultz N, Yaeger R, O'Reilly EM. Keane F, et al. Among authors: singhal a. J Natl Cancer Inst. 2024 May 3:djae095. doi: 10.1093/jnci/djae095. Online ahead of print. J Natl Cancer Inst. 2024. PMID: 38702822