Batt SM - Search Results

1

DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid.

Abrahams KA, Batt SM, Gurcha SS, Veerapen N, Bashiri G, Besra GS. Abrahams KA, et al. Among authors: batt sm. Nat Commun. 2023 Jun 28;14(1):3828. doi: 10.1038/s41467-023-39300-z. Nat Commun. 2023. PMID: 37380634 Free PMC article.

2

Characterization of the Corynebacterium glutamicum deltapimB' deltamgtA double deletion mutant and the role of Mycobacterium tuberculosis orthologues Rv2188c and Rv0557 in glycolipid biosynthesis.

Mishra AK, Batt S, Krumbach K, Eggeling L, Besra GS. Mishra AK, et al. J Bacteriol. 2009 Jul;191(13):4465-72. doi: 10.1128/JB.01729-08. Epub 2009 Apr 24. J Bacteriol. 2009. PMID: 19395496 Free PMC article.

3

Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.

Batt SM, Jabeen T, Mishra AK, Veerapen N, Krumbach K, Eggeling L, Besra GS, Fütterer K. Batt SM, et al. J Biol Chem. 2010 Nov 26;285(48):37741-52. doi: 10.1074/jbc.M110.165407. Epub 2010 Sep 15. J Biol Chem. 2010. PMID: 20843801 Free PMC article.

4

Deletion of manC in Corynebacterium glutamicum results in a phospho-myo-inositol mannoside- and lipoglycan-deficient mutant.

Mishra AK, Krumbach K, Rittmann D, Batt SM, Lee OY, De S, Frunzke J, Besra GS, Eggeling L. Mishra AK, et al. Among authors: batt sm. Microbiology (Reading). 2012 Jul;158(Pt 7):1908-1917. doi: 10.1099/mic.0.057653-0. Epub 2012 Apr 26. Microbiology (Reading). 2012. PMID: 22539165 Free article.

5

Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.

Batt SM, Jabeen T, Bhowruth V, Quill L, Lund PA, Eggeling L, Alderwick LJ, Fütterer K, Besra GS. Batt SM, et al. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11354-9. doi: 10.1073/pnas.1205735109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733761 Free PMC article.

6

Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase.

Batt SM, Cacho Izquierdo M, Castro Pichel J, Stubbs CJ, Vela-Glez Del Peral L, Pérez-Herrán E, Dhar N, Mouzon B, Rees M, Hutchinson JP, Young RJ, McKinney JD, Barros Aguirre D, Ballell L, Besra GS, Argyrou A. Batt SM, et al. ACS Infect Dis. 2015 Dec 11;1(12):615-26. doi: 10.1021/acsinfecdis.5b00065. Epub 2015 Aug 25. ACS Infect Dis. 2015. PMID: 27623058

7

Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes.

Liu R, Lyu X, Batt SM, Hsu MH, Harbut MB, Vilchèze C, Cheng B, Ajayi K, Yang B, Yang Y, Guo H, Lin C, Gan F, Wang C, Franzblau SG, Jacobs WR Jr, Besra GS, Johnson EF, Petrassi M, Chatterjee AK, Fütterer K, Wang F. Liu R, et al. Among authors: batt sm. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):13011-13015. doi: 10.1002/anie.201707324. Epub 2017 Sep 7. Angew Chem Int Ed Engl. 2017. PMID: 28815830 Free PMC article.

8

Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1.

Richter A, Rudolph I, Möllmann U, Voigt K, Chung CW, Singh OMP, Rees M, Mendoza-Losana A, Bates R, Ballell L, Batt S, Veerapen N, Fütterer K, Besra G, Imming P, Argyrou A. Richter A, et al. Sci Rep. 2018 Sep 7;8(1):13473. doi: 10.1038/s41598-018-31316-6. Sci Rep. 2018. PMID: 30194385 Free PMC article.

9

Identification of novel benzothiopyranone compounds against Mycobacterium tuberculosis through scaffold morphing from benzothiazinones.

Li P, Wang B, Zhang X, Batt SM, Besra GS, Zhang T, Ma C, Zhang D, Lin Z, Li G, Huang H, Lu Y. Li P, et al. Among authors: batt sm. Eur J Med Chem. 2018 Dec 5;160:157-170. doi: 10.1016/j.ejmech.2018.09.042. Epub 2018 Sep 17. Eur J Med Chem. 2018. PMID: 30336450

10

Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.

Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z. Zhang L, et al. Among authors: batt sm. Science. 2020 Jun 12;368(6496):1211-1219. doi: 10.1126/science.aba9102. Epub 2020 Apr 23. Science. 2020. PMID: 32327601

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