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Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones.
Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K, Nyabi O, Haigh K, Naessens M, Haenebalcke L, Tuckermann JP, Tjwa M, Carmeliet P, Mandic V, David JP, Behrens A, Nagy A, Carmeliet G, Haigh JJ. Maes C, et al. Among authors: haenebalcke l. EMBO J. 2010 Jan 20;29(2):424-41. doi: 10.1038/emboj.2009.361. Epub 2009 Dec 10. EMBO J. 2010. PMID: 20010698 Free PMC article.
Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells.
Nyabi O, Naessens M, Haigh K, Gembarska A, Goossens S, Maetens M, De Clercq S, Drogat B, Haenebalcke L, Bartunkova S, De Vos I, De Craene B, Karimi M, Berx G, Nagy A, Hilson P, Marine JC, Haigh JJ. Nyabi O, et al. Among authors: haenebalcke l. Nucleic Acids Res. 2009 Apr;37(7):e55. doi: 10.1093/nar/gkp112. Epub 2009 Mar 11. Nucleic Acids Res. 2009. PMID: 19279185 Free PMC article.
The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization.
Goossens S, Janzen V, Bartunkova S, Yokomizo T, Drogat B, Crisan M, Haigh K, Seuntjens E, Umans L, Riedt T, Bogaert P, Haenebalcke L, Berx G, Dzierzak E, Huylebroeck D, Haigh JJ. Goossens S, et al. Among authors: haenebalcke l. Blood. 2011 May 26;117(21):5620-30. doi: 10.1182/blood-2010-08-300236. Epub 2011 Feb 25. Blood. 2011. PMID: 21355089 Free article.
p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway.
Farhang Ghahremani M, Goossens S, Nittner D, Bisteau X, Bartunkova S, Zwolinska A, Hulpiau P, Haigh K, Haenebalcke L, Drogat B, Jochemsen A, Roger PP, Marine JC, Haigh JJ. Farhang Ghahremani M, et al. Among authors: haenebalcke l. Cell Death Differ. 2013 Jul;20(7):888-97. doi: 10.1038/cdd.2013.12. Epub 2013 Mar 1. Cell Death Differ. 2013. PMID: 23449391 Free PMC article.
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.
Goossens S, Radaelli E, Blanchet O, Durinck K, Van der Meulen J, Peirs S, Taghon T, Tremblay CS, Costa M, Farhang Ghahremani M, De Medts J, Bartunkova S, Haigh K, Schwab C, Farla N, Pieters T, Matthijssens F, Van Roy N, Best JA, Deswarte K, Bogaert P, Carmichael C, Rickard A, Suryani S, Bracken LS, Alserihi R, Canté-Barrett K, Haenebalcke L, Clappier E, Rondou P, Slowicka K, Huylebroeck D, Goldrath AW, Janzen V, McCormack MP, Lock RB, Curtis DJ, Harrison C, Berx G, Speleman F, Meijerink JP, Soulier J, Van Vlierberghe P, Haigh JJ. Goossens S, et al. Among authors: haenebalcke l. Nat Commun. 2015 Jan 7;6:5794. doi: 10.1038/ncomms6794. Nat Commun. 2015. PMID: 25565005 Free PMC article.
Strategies to rescue the consequences of inducible arginase-1 deficiency in mice.
Ballantyne LL, Sin YY, St Amand T, Si J, Goossens S, Haenebalcke L, Haigh JJ, Kyriakopoulou L, Schulze A, Funk CD. Ballantyne LL, et al. Among authors: haenebalcke l. PLoS One. 2015 May 4;10(5):e0125967. doi: 10.1371/journal.pone.0125967. eCollection 2015. PLoS One. 2015. PMID: 25938595 Free PMC article.
14 results